Pdpn | podoplanin

GeneMGI:103098Synonyms: PA2.26, OTS-8, +4 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating cholesterol level	1 supporting dataset	Pdpn^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.86x10^-5
absent vibrissae	1 supporting dataset	Pdpn^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.96x10^-8
increased circulating calcium level	1 supporting dataset	Pdpn^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.47x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Pdpn^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdpn.

Associated images

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Histopathology

There is no histopathology data found for Pdpn.

IMPC related publications

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External links

No external links available for Pdpn.

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*Pdpn^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pdpn^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pdpn^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Pdpn^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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