Stat4 | signal transducer and activator of transcription 4
GeneMGI:103062
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Renal/urinary system
15 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small kidney | 1 supporting dataset | Stat4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| cataract | 1 supporting dataset | Stat4em1(IMPC)Mbp | homozygote | Early adult | 6.35x10-5 | ||
| abnormal vitreous body morphology | 1 supporting dataset | Stat4em1(IMPC)Mbp | homozygote | Early adult | 5.99x10-5 | ||
| cornea opacity | 1 supporting dataset | Stat4em1(IMPC)Mbp | homozygote | Early adult | 1.72x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Stat4em1(IMPC)Mbp | homozygote | Early adult | N/A * |
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Human diseases caused by Stat4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Stat4.
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| Stat4em1(IMPC)Mbp | Exon Deletion | | mouse |
| Stat4tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Stat4tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |