Stat4 | signal transducer and activator of transcription 4

GeneMGI:103062

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Renal/urinary system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small kidney	1 supporting dataset	Stat4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Stat4^em1(IMPC)Mbp	homozygote	Early adult	6.35x10^-5
abnormal vitreous body morphology	1 supporting dataset	Stat4^em1(IMPC)Mbp	homozygote	Early adult	5.99x10^-5
cornea opacity	1 supporting dataset	Stat4^em1(IMPC)Mbp	homozygote	Early adult	1.72x10^-5
abnormal kidney morphology	1 supporting dataset	Stat4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stat4.

Associated images

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Histopathology

There is no histopathology data found for Stat4.

IMPC related publications

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External links

No external links available for Stat4.

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*Stat4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Stat4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stat4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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