Epb41l1 | erythrocyte membrane protein band 4.1 like 1

GeneMGI:103010Synonyms: 4.1N, Epb4.1l1

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.11x10^-7
improved glucose tolerance	2 supporting datasets	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.54x10^-7
decreased grip strength	2 supporting datasets	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.34x10^-12
increased circulating aspartate transaminase level	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.77x10^-5
hyperactivity	10 supporting datasets	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.55x10^-31
increased startle reflex	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.8x10^-6
abnormal iris pigmentation	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.62x10^-7
abnormal locomotor behavior	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.39x10^-5
increased bone mineral content	1 supporting dataset	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.65x10^-5
decreased thigmotaxis	2 supporting datasets	Epb41l1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.27x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Epb41l1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Epb41l1.

IMPC related publications

Loading...

External links

No external links available for Epb41l1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Epb41l1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Epb41l1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Epb41l1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes