Srprb | signal recognition particle receptor, B subunit
GeneMGI:102964
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues
| decreased mean corpuscular volume | 1 supporting dataset | Srprbtm2b(EUCOMM)Hmgu | heterozygote | Early adult | 1.41x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Srprbtm2b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased circulating creatinine level | 1 supporting dataset | Srprbtm2b(EUCOMM)Hmgu | heterozygote | Early adult | 2.06x10-7 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Srprbtm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Srprbtm2b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * |
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External links
No external links available for Srprb.
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| Srprbtm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Srprbtm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Srprbtm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |