Prss2 | serine protease 2
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
| limb grasping | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 6.81x10-8 | ||
| decreased bone mineral content | 2 supporting datasets | Prss2tm1.1(KOMP)Vlcg | homozygote | Early adult | 8.39x10-7 | ||
| decreased circulating phosphate level | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 7.49x10-5 | ||
| impaired righting response | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 2.36x10-7 | ||
| decreased locomotor activity | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 7.7x10-5 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 1.5x10-5 | ||
| decreased bone mineral density | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.59x10-6 | ||
| increased exploration in new environment | 1 supporting dataset | Prss2tm1.1(KOMP)Vlcg | homozygote | Late adult | 2.12x10-5 |
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External links
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| Prss2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Prss2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Prss2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Prss2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |