Pcnt | pericentrin (kendrin)

GeneMGI:102722Synonyms: Pcnt2, m275Asp, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Integument Embryo Growth/size/body region Vision/eye Mortality/aging Renal/urinary system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Pcnt^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	6.35x10^-5
abnormal skin morphology	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
decreased body length	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	6.44x10^-6
small testis	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
microphthalmia	1 supporting dataset	Pcnt^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Pcnt^em1(IMPC)Mbp	heterozygote	Early adult	5.99x10^-5
embryonic growth retardation	1 supporting dataset	Pcnt^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pcnt.

Associated images

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Histopathology

There is no histopathology data found for Pcnt.

IMPC related publications

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External links

No external links available for Pcnt.

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*Pcnt^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Pcnt^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pcnt^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pcnt^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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