Ptprm | protein tyrosine phosphatase receptor type M

GeneMGI:102694Synonyms: RPTPmu

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetPtprmem1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal heart morphology1 supporting datasetPtprmem1(IMPC)RbrchomozygoteLate adultN/A * 
abnormal circulating glucose level1 supporting datasetPtprmem1(IMPC)RbrchomozygoteLate adult1.75x10-5 
increased circulating creatine kinase level1 supporting datasetPtprmem1(IMPC)RbrchomozygoteEarly adult4.12x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ptprmem1(IMPC)RbrcExon Deletionmouse
Ptprmtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ptprmtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ptprmtm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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