Wnt11 | wingless-type MMTV integration site family, member 11

GeneMGI:101948

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Growth/size/body region Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased body length	1 supporting dataset	Wnt11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.33x10^-5
abnormal kidney morphology	2 supporting datasets	Wnt11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Wnt11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Wnt11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased blood urea nitrogen level	1 supporting dataset	Wnt11^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.76x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wnt11.

Associated images

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Histopathology

There is no histopathology data found for Wnt11.

IMPC related publications

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External links

No external links available for Wnt11.

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*Wnt11^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Wnt11^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Wnt11^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Wnt11^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Wnt11^{tm299234(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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