Hnrnpd | heterogeneous nuclear ribonucleoprotein D

GeneMGI:101947Synonyms: Hnrpd, Auf1

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased basophil cell number	2 supporting datasets	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	8.46x10^-25
decreased leukocyte cell number	1 supporting dataset	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.44x10^-6
decreased lymphocyte cell number	1 supporting dataset	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.21x10^-9
decreased locomotor activity	2 supporting datasets	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	1.34x10^-5
increased eosinophil cell number	2 supporting datasets	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.15x10^-8
abnormal behavior	1 supporting dataset	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.48x10^-5
increased anxiety-related response	1 supporting dataset	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	5.39x10^-5
increased thigmotaxis	2 supporting datasets	Hnrnpd^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hnrnpd.

Associated images

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Histopathology

There is no histopathology data found for Hnrnpd.

IMPC related publications

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External links

No external links available for Hnrnpd.

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*Hnrnpd^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hnrnpd^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hnrnpd^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Hnrnpd^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Hnrnpd^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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