Aldoc | aldolase C, fructose-bisphosphate

GeneMGI:101863Synonyms: Scrg2, Aldo3, +2 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Hearing/vestibular/ear Respiratory system Behavior/neurological Renal/urinary system

17 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased pulmonary ventilation2 supporting datasetsAldoctm1.1(KOMP)VlcghomozygoteEarly adult6.64x10-13 
abnormal auditory brainstem response1 supporting datasetAldoctm1.1(KOMP)VlcghomozygoteEarly adult2.9x10-6 
hyperactivity2 supporting datasetsAldoctm1.1(KOMP)VlcghomozygoteEarly adult3.21x10-5 
increased pulmonary respiratory rate1 supporting datasetAldoctm1.1(KOMP)VlcghomozygoteEarly adult2.07x10-8 
abnormal kidney morphology1 supporting datasetAldoctm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aldoctm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Aldoctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Aldoctm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Aldoctm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aldoctm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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