Usp15 | ubiquitin specific peptidase 15

GeneMGI:101857Synonyms: Gcap18, E430033I05Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased leukocyte cell number1 supporting datasetUsp15em1(IMPC)MarchomozygoteEarly adult6.14x10-6 
decreased locomotor activity2 supporting datasetsUsp15em1(IMPC)MarchomozygoteEarly adult6.86x10-5 
increased basophil cell number2 supporting datasetsUsp15em1(IMPC)MarchomozygoteEarly adult1.1x10-26 
increased circulating sodium level1 supporting datasetUsp15tm1b(EUCOMM)WtsihomozygoteEarly adult2.92x10-5 
increased mean platelet volume1 supporting datasetUsp15tm1b(EUCOMM)WtsihomozygoteEarly adult4.94x10-5 
decreased circulating glucose level1 supporting datasetUsp15tm1b(EUCOMM)WtsihomozygoteEarly adult9.54x10-5 
increased bone mineral content1 supporting datasetUsp15tm1b(EUCOMM)WtsihomozygoteEarly adult1.77x10-5 
improved glucose tolerance1 supporting datasetUsp15em1(IMPC)MarchomozygoteEarly adult7.38x10-6 
increased eosinophil cell number2 supporting datasetsUsp15em1(IMPC)MarchomozygoteEarly adult3.47x10-18 
decreased total body fat amount1 supporting datasetUsp15tm1b(EUCOMM)WtsihomozygoteEarly adult3.03x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp15em1(IMPC)MarcDeletionmouse
Usp15em3(IMPC)MarcDeletionmouse
Usp15tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Usp15tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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