Usp45 | ubiquitin specific petidase 45

GeneMGI:101850Synonyms: Gcap7, 3110003C05Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased eosinophil cell number2 supporting datasetsUsp45em1(IMPC)MarchomozygoteEarly adult3.56x10-9 
increased basophil cell number2 supporting datasetsUsp45em1(IMPC)MarchomozygoteEarly adult4.18x10-20 
decreased neutrophil cell number1 supporting datasetUsp45em1(IMPC)HhomozygoteEarly adult4.75x10-5 
increased monocyte cell number1 supporting datasetUsp45em1(IMPC)MarchomozygoteEarly adult2.79x10-5 
increased mean corpuscular hemoglobin1 supporting datasetUsp45em1(IMPC)MarchomozygoteEarly adult4.33x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetUsp45em1(IMPC)MarchomozygoteEarly adult7.86x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Usp45em1(IMPC)HExon Deletionmouse
Usp45em1(IMPC)MarcDeletionmouse

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