Nes | nestin

GeneMGI:101784Synonyms: Marc2, Ifaprc2, +2 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Cardiovascular system

14 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
52Embryo tissues

Phenotypes

increased heart weight1 supporting datasetNestm1b(KOMP)WtsihomozygoteEarly adult6.92x10-6 
increased circulating chloride level1 supporting datasetNestm1b(KOMP)WtsihomozygoteEarly adult2.48x10-5 
decreased circulating cholesterol level1 supporting datasetNestm1b(KOMP)WtsihomozygoteEarly adult9.72x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nestm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Nestm115801(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Nestm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nestm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Nestm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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