Mcl1 | myeloid cell leukemia sequence 1
Physiological systems
21 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
3 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small spleen | 2 supporting datasets | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased mean corpuscular volume | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | 3.57x10-10 | ||
| embryonic growth retardation | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | E9.5 | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Mcl1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Mcl1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| anophthalmia | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal eye morphology | 2 supporting datasets | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Mcl1em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Mcl1.
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| Mcl1em1(IMPC)Mbp | Exon Deletion | | mouse |