Sfswap | splicing factor SWAP
Physiological systems
17 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging Cardiovascular system
13 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| prolonged RR interval | 1 supporting dataset | Sfswapem1(IMPC)J | heterozygote | Early adult | 6.25x10-6 | ||
| decreased grip strength | 1 supporting dataset | Sfswapem1(IMPC)J | heterozygote | Early adult | 8.09x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Sfswapem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased heart rate | 1 supporting dataset | Sfswapem1(IMPC)J | heterozygote | Early adult | 2.58x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Sfswapem1(IMPC)J | homozygote | Early adult | N/A * | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Sfswapem1(IMPC)J | heterozygote | Early adult | 4.45x10-8 |
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External links
No external links available for Sfswap.
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| Sfswapem1(IMPC)J | Exon Deletion | | mouse |
| Sfswaptm363458(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |