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CRISPR is an extremely useful tool for mouse models but is not ready for use on human embryos

A researcher in China claims to have produced the first genome-edited babies through using CRISPR. The IMPC uses the CRISPR/Cas9…

Published: 28 Nov 2018

Exploring the therapeutic potential of CRISPR/Cas9 for the treatment of PelizaeusMerzbacher Disease

ASHG 2018 Annual Meeting – research using mouse models Guest post by Eleonora Maino (ASHG poster: Wednesday 2-3pm, poster number 1107)…

Published: 17 Oct 2018

Connexin 47 gain-of function CRISPR mouse model

ASHG 2018 Annual Meeting – research using mouse models Guest post by Robert Erickson (ASHG poster: Wed Oct 17th, 2:00pm…

Published: 11 Oct 2018

New CRISPR technique skips over portions of genes that cause disease

In a new study in cells, University of Illinois researchers have adapted CRISPR gene-editing technology to cause the cell's internal…

Published: 17 Aug 2018

New technology improves CRISPR-Cas9 gene editing in mosquitoes

A technology designed to improve CRISPR-Cas9 gene editing in mosquitoes and other arthropods succeeds with a high degree of efficiency,…

Published: 14 Aug 2018

Using Cas12a instead of Cas9 may improve the gene-editing tool CRISPR

Among the most significant scientific advances in recent years are the discovery and development of new ways to genetically modify…

Published: 3 Aug 2018

Two new articles highlight the usefulness and intricacies of CRISPR/Cas9 technology

CRISPR/Cas9 has revolutionised genetic research, with seemingly no end to its potential applications. Until recently genome engineering relied on the…

Published: 12 Jul 2018

CRISPR gene drives tested in mice for the first time

As highlighted in a recent post, there are a variety of new applications for CRISPR technology. A study out this week describes…

Published: 11 Jul 2018

New research suggests laboratory mouse data can help in wildlife conservation

The International Mouse Phenotyping Consortium (IMPC) has been predominantly interested in using mouse models to understand human health and disease.…

Published: 25 May 2018

Cytoplasmic Microinjection to generate CRISPR mediated mutations

[embed]https://www.youtube.com/watch?v=4K4RDG1q6z8&t=97s[/embed] Brendan Doe talks about his work in using Cytoplasmic Microinjection to generate CRISPR mediated mutations. This method has recently…

Published: 20 Apr 2018

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