Plod1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

GeneMGI:99907Synonyms: lysyl hydroxylase 1, LH1, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Nervous system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	2 supporting datasets	Plod1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.48x10^-6
decreased grip strength	4 supporting datasets	Plod1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.49x10^-31

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plod1.

Associated images

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Histopathology

There is no histopathology data found for Plod1.

IMPC related publications

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External links

No external links available for Plod1.

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*Plod1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Plod1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Plod1^{tm44515(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes