Otp | orthopedia homeobox

GeneMGI:99835

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Mortality/aging

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased mean platelet volume	1 supporting dataset	Otp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.21x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Otp^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating iron level	1 supporting dataset	Otp^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.64x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Otp.

Associated images

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Histopathology

There is no histopathology data found for Otp.

IMPC related publications

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External links

No external links available for Otp.

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*Otp^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Otp^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Otp^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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