Lhx1 | LIM homeobox protein 1

GeneMGI:99783Synonyms: Lim1

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased startle reflex	4 supporting datasets	Lhx1^{tm1e(EUCOMM)Wtsi}	heterozygote	Early adult	3.17x10^-6
decreased circulating alkaline phosphatase level	1 supporting dataset	Lhx1^{tm1e(EUCOMM)Wtsi}	heterozygote	Early adult	4.59x10^-5
increased CD8-positive, alpha-beta T cell number	1 supporting dataset	Lhx1^{tm1e(EUCOMM)Wtsi}	heterozygote	Early adult	6.38x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lhx1.

Associated images

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Histopathology

There is no histopathology data found for Lhx1.

IMPC related publications

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External links

No external links available for Lhx1.

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*Lhx1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Lhx1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Lhx1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	mouse

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