Kdm5c | lysine demethylase 5C
Physiological systems
7 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
6 No significant impact
17 Not tested
Data collections
Gene metrics:1Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Kdm5ctm1d(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
| | | | | | | | | | |
Human diseases caused by Kdm5c mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Kdm5c.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Kdm5ctm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Kdm5ctm1c(EUCOMM)Hmgu | Wild type floxed exon (post-Flp) | | mouse |
| Kdm5ctm1d(EUCOMM)Hmgu | Deletion allele (post-Flp and Cre with no reporter) | | mouse |
| Kdm5ctm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Kdm5ctm40984(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |