Ephb2 | Eph receptor B2
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Growth/size/body region Hematopoietic system Behavior/neurological
16 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small spleen | 1 supporting dataset | Ephb2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Ephb2em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased exploration in new environment | 1 supporting dataset | Ephb2em1(IMPC)Mbp | homozygote | Early adult | 9.25x10-6 |
| | | | | | | | | | |
Human diseases caused by Ephb2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ephb2.
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| Ephb2em1(IMPC)Mbp | Exon Deletion | | mouse |
| Ephb2tm232764(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |