Nr3c2 | nuclear receptor subfamily 3, group C, member 2

GeneMGI:99459Synonyms: mineralocorticoid receptor, Mlr, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	1 supporting dataset	Nr3c2^Nr3c2	heterozygote	Early adult	2.31x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Nr3c2^Nr3c2	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Nr3c2^Nr3c2	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nr3c2.

Associated images

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Histopathology

There is no histopathology data found for Nr3c2.

IMPC related publications

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External links

No external links available for Nr3c2.

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*Nr3c2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nr3c2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Nr3c2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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