Arf4 | ADP-ribosylation factor 4
GeneMGI:99433
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Immune system Embryo Growth/size/body region Hematopoietic system Mortality/aging
17 No significant impact
2 Not tested
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:43Adult tissues
30Embryo tissues
| abnormal spleen morphology | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Arf4tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.89x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| enlarged spleen | 1 supporting dataset | Arf4tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * |
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External links
No external links available for Arf4.
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| Arf4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Arf4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Arf4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |