Uros | uroporphyrinogen III synthase

GeneMGI:98917Synonyms: hydroxymethylbilane hydrolyase (cyclizing), uroporphyrinogen-III synthase, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Uros^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased leukocyte cell number	1 supporting dataset	Uros^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Uros.

Associated images

Loading...

Histopathology

There is no histopathology data found for Uros.

IMPC related publications

Loading...

External links

No external links available for Uros.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Uros^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Uros^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes