Pgc | progastricsin (pepsinogen C)

GeneMGI:98909Synonyms: 2210410L06Rik, Upg-1, +1 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged heart1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
small testis1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetPgcem1(IMPC)CcpczhomozygoteEarly adult2.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pgcem1(IMPC)CcpczExon Deletionmouse
Pgctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Pgctm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Pgctm402444(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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