Surf4 | surfeit gene 4
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| impaired glucose tolerance | 1 supporting dataset | Surf4em1(IMPC)J | heterozygote | Early adult | 1.36x10-9 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Surf4em1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased circulating phosphate level | 1 supporting dataset | Surf4em1(IMPC)J | heterozygote | Early adult | 6.2x10-5 |
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Human diseases caused by Surf4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Surf4.
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| Surf4em1(IMPC)J | Exon Deletion | | mouse |
| Surf4tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Surf4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Surf4tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Surf4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Surf4tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Surf4tm26415(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |