Sox13 | SRY (sex determining region Y)-box 13

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular volume1 supporting datasetSox13tm1a(EUCOMM)WtsihomozygoteEarly adult7.85x10-10 
decreased erythrocyte cell number1 supporting datasetSox13tm1a(EUCOMM)WtsihomozygoteEarly adult5.47x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetSox13tm1a(EUCOMM)WtsihomozygoteEarly adult2.21x10-8 
increased startle reflex5 supporting datasetsSox13tm1a(EUCOMM)WtsihomozygoteEarly adult2.53x10-9 
abnormal tail movements1 supporting datasetSox13tm1a(EUCOMM)WtsihomozygoteEarly adult3.23x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sox13tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Sox13tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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