Spi1 | Spi-1 proto-oncogene
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Hematopoietic system Mortality/aging Cardiovascular system
18 No significant impact
3 Not tested
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
| hemorrhage | 1 supporting dataset | Spi1tm2b(EUCOMM)Wtsi | homozygote | E15.5 | N/A * | ||
| decreased erythrocyte cell number | 1 supporting dataset | Spi1tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 4.91x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Spi1tm2b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased mean corpuscular volume | 1 supporting dataset | Spi1tm2b(EUCOMM)Wtsi | heterozygote | Early adult | 1.83x10-5 |
| | | | | | | | | | |
External links
No external links available for Spi1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Spi1em1(IMPC)Wtsi | Point Mutation | | mouse |
| Spi1tm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Spi1tm199198(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Spi1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Spi1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Spi1tm2(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Spi1tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Spi1tm2b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |