Ccl3 | C-C motif chemokine ligand 3
Physiological systems
17 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
16 No significant impact
7 Not tested
Data collections
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating total protein level | 1 supporting dataset | Ccl3em1(IMPC)H | homozygote | Early adult | 5.53x10-7 | ||
| decreased circulating serum albumin level | 1 supporting dataset | Ccl3em1(IMPC)H | homozygote | Early adult | 3.06x10-7 |
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Human diseases caused by Ccl3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Ccl3.
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| Ccl3em1(IMPC)H | Inter-exon deletion | | mouse |
| Ccl3em2(IMPC)H | Inter-exon deletion | | mouse |
| Ccl3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Ccl3tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ccl3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |