Rmrp | RNA component of mitochondrial RNAase P

GeneMGI:97937Synonyms: Rmrpr, RNase MRP

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:9Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased circulating cholesterol level1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adult9.8x10-10 
increased lymphocyte cell number1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adult4.54x10-5 
abnormal spleen morphology2 supporting datasetsRmrpem1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased circulating HDL cholesterol level1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adult5.63x10-11 
small heart1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased kidney weight1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adult9.05x10-5 
enhanced cued conditioning behavior1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adult8.85x10-6 
abnormal heart morphology1 supporting datasetRmrpem1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rmrpem1(IMPC)CcpczWhole-gene deletionmouse

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