Pou1f1 | POU domain, class 1, transcription factor 1
Physiological systems
14 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Mortality/aging
13 No significant impact
10 Not tested
Data collections
Gene metrics:2Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Pou1f1em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pou1f1em1(IMPC)Bay | homozygote | Early adult | N/A * |
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Human diseases caused by Pou1f1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pou1f1.
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| Pou1f1em1(IMPC)Bay | Exon Deletion | | mouse |
| Pou1f1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Pou1f1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pou1f1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |