Prf1 | perforin 1 (pore forming protein)

GeneMGI:97551Synonyms: Pfp, Pfn, +2 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Hematopoietic system

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

6Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



decreased mean corpuscular hemoglobin concentration	1 supporting dataset		Prf1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult		2.97x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Prf1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Prf1.

IMPC related publications

Loading...

External links

No external links available for Prf1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Prf1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Prf1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Prf1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Prf1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes