Pdha2 | pyruvate dehydrogenase E1 alpha 2
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Immune system Hematopoietic system
16 No significant impact
6 Not tested
Data collections
Gene metrics:1Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal spleen morphology | 2 supporting datasets | Pdha2em1(IMPC)Bay | homozygote | Early adult | N/A * |
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Human diseases caused by Pdha2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pdha2.
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| Pdha2em1(IMPC)Bay | Exon Deletion | | mouse |
| Pdha2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pdha2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |