Nf1 | neurofibromin 1

GeneMGI:97306Synonyms: neurofibromin, Dsk9, +2 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

14Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, complete penetrance	2 supporting datasets		Nf1^{tm1a(KOMP)Wtsi}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nf1.

Associated images

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Histopathology

There is no histopathology data found for Nf1.

IMPC related publications

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External links

No external links available for Nf1.

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*Nf1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nf1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nf1^{tm38164(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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