Mos | Moloney sarcoma oncogene

GeneMGI:97052Synonyms: c-mos

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Skeleton Cardiovascular system

15 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetMostm1.1(KOMP)VlcghomozygoteEarly adult4.21x10-5 
increased heart weight1 supporting datasetMostm1.1(KOMP)VlcghomozygoteEarly adult2.14x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
brainheterozygoten/a0% (0/2)0.86% (5/579)
brainstemheterozygoten/a0% (0/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
epididymisheterozygoten/a0% (0/1)87.5% (21/24)
esophagusheterozygoten/a0% (0/2)1.67% (7/419)
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Histopathology

IMPC related publications

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Mostm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Mostm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Mostm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Mostm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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