Mme | membrane metallo endopeptidase

GeneMGI:97004Synonyms: CD10, 6030454K05Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

19 No significant impact

4 Not tested

Gene metrics:1Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating phosphate level1 supporting datasetMmeem1(IMPC)MbphomozygoteEarly adult6.43x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Mme mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Mmeem1(IMPC)MbpInter-exon deletionmouse
Mmetm300418(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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