Maf | MAF bZIP transcription factor
Physiological systems
22 / 24 physiological systems tested
14 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Nervous system Vision/eye Liver/biliary system Behavior/neurological Mortality/aging
8 No significant impact
2 Not tested
Data collections
Gene metrics:29Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| microphthalmia | 1 supporting dataset | Mafem1(IMPC)Mbp | heterozygote | E15.5 | N/A * | ||
| enlarged spleen | 1 supporting dataset | Mafem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| enlarged spleen | 2 supporting datasets | Mafem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Mafem1(IMPC)Mbp | homozygote | E15.5 | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Mafem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| abnormal vitreous body morphology | 1 supporting dataset | Mafem1(IMPC)Mbp | heterozygote | Late adult | 3.22x10-5 | ||
| abnormal kidney morphology | 1 supporting dataset | Mafem1(IMPC)Mbp | heterozygote | Late adult | N/A * | ||
| decreased prepulse inhibition | 6 supporting datasets | Mafem1(IMPC)Mbp | heterozygote | Early adult | 3.66x10-9 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Mafem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| enlarged kidney | 1 supporting dataset | Mafem1(IMPC)Mbp | heterozygote | Late adult | N/A * |
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External links
No external links available for Maf.
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| Mafem1(IMPC)Mbp | Deletion | | mouse |