Lox | lysyl oxidase

GeneMGI:96817Synonyms: TSC-160, ras recision gene (rrg)

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Integument Embryo Limbs/digits/tail Skeleton Mortality/aging Renal/urinary system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta morphology	1 supporting dataset	Lox^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Lox^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Lox^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal caudal vertebrae morphology	1 supporting dataset	Lox^em1(IMPC)Mbp	heterozygote	Early adult	1.19x10^-6
abnormal kidney morphology	1 supporting dataset	Lox^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Lox^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lox.

Associated images

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Histopathology

There is no histopathology data found for Lox.

IMPC related publications

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External links

No external links available for Lox.

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*Lox^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Lox^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

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