Lhcgr | luteinizing hormone/choriogonadotropin receptor
Physiological systems
13 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Digestive/alimentary Nervous system Respiratory system Liver/biliary system Hematopoietic system Cardiovascular system
5 No significant impact
11 Not tested
Data collections
Gene metrics:11Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| small liver | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased lymphocyte cell number | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | 8x10-6 | ||
| small spleen | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| increased leukocyte cell number | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | 1.08x10-11 | ||
| decreased brain size | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| small thymus | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| small heart | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| thrombocytopenia | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | 6.48x10-6 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | 8.27x10-5 | ||
| small stomach | 1 supporting dataset | Lhcgrtm1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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Human diseases caused by Lhcgr mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Lhcgr.
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