Krt1 | keratin 1

GeneMGI:96698Synonyms: Krt-2.1, Krt2-1

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Respiratory system Hematopoietic system Behavior/neurological Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

14Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	2 supporting datasets	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased effector memory CD8-positive, alpha-beta T cell number	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.37x10^-8
abnormal thymus morphology	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small epididymis	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased grip strength	4 supporting datasets	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	9x10^-10
abnormal epididymis morphology	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	2 supporting datasets	Krt1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Krt1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Krt1.

IMPC related publications

Loading...

External links

No external links available for Krt1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Krt1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Krt1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Krt1^{tm96263(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes