Kcnc1 | potassium voltage gated channel, Shaw-related subfamily, member 1

GeneMGI:96667Synonyms: Kcr2-1, Shaw, +5 more

Physiological systems

10 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

9 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity9 supporting datasetsKcnc1em4(IMPC)HhomozygoteEarly adult6.89x10-16 
increased vertical activity1 supporting datasetKcnc1em4(IMPC)HhomozygoteEarly adult4.72x10-9 
increased exploration in new environment1 supporting datasetKcnc1em4(IMPC)HhomozygoteEarly adult5.28x10-11 
decreased anxiety-related response1 supporting datasetKcnc1em4(IMPC)HhomozygoteEarly adult2.84x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnc1em4(IMPC)HIndelmouse
Kcnc1em5(IMPC)HIndelmouse
Kcnc1tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kcnc1tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Kcnc1tm94178(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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