Itpr3 | inositol 1,4,5-triphosphate receptor 3
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Growth/size/body region Vision/eye
17 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal skin morphology | 2 supporting datasets | Itpr3em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased body length | 1 supporting dataset | Itpr3em1(IMPC)Mbp | homozygote | Early adult | 4.55x10-5 | ||
| cornea opacity | 1 supporting dataset | Itpr3em1(IMPC)Mbp | homozygote | Early adult | 8.22x10-5 |
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Human diseases caused by Itpr3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Itpr3.
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| Itpr3em1(IMPC)Mbp | Exon Deletion | | mouse |
| Itpr3tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |