Itpr1 | inositol 1,4,5-trisphosphate receptor 1
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Embryo Growth/size/body region Mortality/aging
15 No significant impact
5 Not tested
Gene metrics:4Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
51Embryo tissues
| abnormal embryo size | 1 supporting dataset | Itpr1tm1.1(NCOM)Mfgc | homozygote | E9.5 | N/A * | ||
| small epididymis | 1 supporting dataset | Itpr1tm1.1(NCOM)Mfgc | heterozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Itpr1tm1.1(NCOM)Mfgc | homozygote | E9.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 2 supporting datasets | Itpr1tm1.1(NCOM)Mfgc | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Itpr1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Itpr1tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Itpr1tm1.1(NCOM)Mfgc | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Itpr1tm357032(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |