Itgb5 | integrin beta 5

GeneMGI:96614Synonyms: [b]5A, [b]-5, +5 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	4 supporting datasets	Itgb5^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	3.91x10^-10
abnormal eye morphology	1 supporting dataset	Itgb5^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	3.52x10^-9
decreased locomotor activity	1 supporting dataset	Itgb5^{tm1e(EUCOMM)Wtsi}	homozygote	Early adult	5.01x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Itgb5.

Associated images

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Histopathology

There is no histopathology data found for Itgb5.

IMPC related publications

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External links

No external links available for Itgb5.

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*Itgb5^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Itgb5^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell mouse
*Itgb5^{tm46356(L1L2_gt2_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes