Itgam | integrin alpha M
Physiological systems
15 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Hematopoietic system
14 No significant impact
9 Not tested
Data collections
Gene metrics:1Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean corpuscular hemoglobin | 1 supporting dataset | Itgamem1(IMPC)Wtsi | homozygote | Early adult | 8.45x10-6 |
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Human diseases caused by Itgam mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Itgam.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Itgamem1(IMPC)Wtsi | Deletion | | mouse |
| Itgamtm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |