Il12b | interleukin 12b

GeneMGI:96540Synonyms: IL-12 p40, IL-23 subunit p40, +2 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



impaired glucose tolerance	1 supporting dataset		Il12b^em1(IMPC)H	homozygote	Early adult		3.17x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il12b.

Associated images

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Histopathology

There is no histopathology data found for Il12b.

IMPC related publications

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External links

No external links available for Il12b.

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*Il12b^em1(IMPC)H*	Inter-exon deletion	‌	mouse
*Il12b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Il12b^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Il12b^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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