Il10ra | interleukin 10 receptor, alpha

GeneMGI:96538Synonyms: CDw210, mIL-10R, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hearing/vestibular/ear Hematopoietic system Behavior/neurological

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



improved glucose tolerance	1 supporting dataset	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.89x10^-6
decreased blood urea nitrogen level	1 supporting dataset	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.37x10^-5
decreased lymphocyte cell number	1 supporting dataset	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.09x10^-5
decreased startle reflex	1 supporting dataset	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.9x10^-5
abnormal auditory brainstem response	2 supporting datasets	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.27x10^-7
increased neutrophil cell number	2 supporting datasets	Il10ra^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.92x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il10ra.

Associated images

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Histopathology

There is no histopathology data found for Il10ra.

IMPC related publications

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External links

No external links available for Il10ra.

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*Il10ra^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Il10ra^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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