Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1)

GeneMGI:95819Synonyms: M100174, Nmdar, +4 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
6Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

thrombocytopenia1 supporting datasetGrin1tm1a(EUCOMM)WtsiheterozygoteEarly adult5.35x10-6 
decreased circulating potassium level1 supporting datasetGrin1tm1a(EUCOMM)WtsiheterozygoteEarly adult2.32x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Grin1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Grin1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Grin1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Grin1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Grin1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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