Grik4 | glutamate receptor, ionotropic, kainate 4

GeneMGI:95817Synonyms: KA1, GluRgamma1, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Nervous system Vision/eye

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	4 supporting datasets	Grik4^em1(IMPC)Mbp	homozygote	Early adult	2.86x10^-7
decreased lean body mass	1 supporting dataset	Grik4^em1(IMPC)Mbp	homozygote	Early adult	4.31x10^-5
increased total body fat amount	1 supporting dataset	Grik4^em1(IMPC)Mbp	homozygote	Early adult	4.28x10^-5
abnormal eye morphology	1 supporting dataset	Grik4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
impaired glucose tolerance	2 supporting datasets	Grik4^em1(IMPC)Mbp	homozygote	Early adult	9.3x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Grik4.

Associated images

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Histopathology

There is no histopathology data found for Grik4.

IMPC related publications

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External links

No external links available for Grik4.

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*Grik4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Grik4^{tm44502(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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