Gsr | glutathione reductase
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Growth/size/body region Renal/urinary system
17 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged kidney | 1 supporting dataset | Gsrem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Gsrem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Gsrem1(IMPC)Mbp | homozygote | Early adult | N/A * |
| | | | | | | | | | |
Human diseases caused by Gsr mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Gsr.
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| Gsrem1(IMPC)Mbp | Exon Deletion | | mouse |
| Gsrtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gsrtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Gsrtm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gsrtm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Gsrtm33624(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |